Scientific instruments maker Bruker has launched the neofleX Imaging Profiler, a matrix-assisted laser desorption/ionisation (MALDI)- time-of-flight (TOF)/TOF system for spatial biology mass spectrometry imaging (MSI) applications.
The neofleX Imaging Profiler is said to be a versatile and easy-to-use multiomics MSI system designed for biopharma, translational, and clinical researchers.
The system facilitates the generation of OME-TIFF files through the new SCiLS Scope software.
The neofleX Imaging Profiler MALDI-TOF/TOF mass spectrometer is equipped with Bruker’s proprietary 10 kHz smartbeam 3D laser. The laser ensures pixel accuracy, along with advanced imaging detectors for longitudinal performance in both linear and reflector modes.
Additionally, neofleX offers a TOF/TOF configuration featuring an enhanced fragmentation module to boost sensitivity, speed, and sequence coverage.
Bruker said that the latest offering is compatible with MALDI HiPLEX-IHC workflow and MALDI-ISH technique. It can also be integrated with Bruker’s MALDI imaging software and consumables ecosystems like IntelliSlides and SCiLS autopilot.
The neofleX offers enhanced insight per pixel through multiomic spatial biology data from tissue sections. This allows to correlate targeted proteins with glycans, metabolites, lipids, endogenous peptides, xenobiotics, and now RNA/DNA.
Bruker life sciences mass spectrometry division MSI vice president Michael Easterling said: “The neofleX offers unique combination of outstanding performance, multimodal software and workflows on the benchtop for a wide range of biopharma and clinical researchers.
“Additionally, neofleX brings novel capabilities to spatial biology, including spatial proteomics combined with unique multiomics correlations for developing actionable biological insights.”
The scientific instruments maker has also announced the launch of its timsTOF Ultra 2 system.
The timsTOF Ultra 2 system is said to have increased sample loading flexibility and enhanced sensitivity for deep profiling of small cells and subcellular organelles.
Bruker is also launching the new Spectronaut 19 (SN19) software and the novel PreOmics ENRICHplus kit for 4D-Proteomics.
Additionally, the company has introduced the OmniScape software for top-down sequence confirmation. It can also be used for de novo sequencing of proteoforms, dissociated in the mass spectrometer.
Other new products launched by the firm include a real-time glycoproteomic software called GlycoScape. The software will help advance glycobiology in translational and clinical research.
